Lyme Disease vs Mono

zoomed up photo of tick on green leaf

At one of our many locations (DOCS Urgent Care center in Fairfield, CT), we get a lot of questions about Lyme disease. We hope to resolve your concerns so that you can feel confident in treating whatever condition you have.

Many of you know the defeating side effects of contracting Lyme disease or mononucleosis (“mono”). Lyme disease is bacterial and spread through the bacteria, Borrelia burgdorferi, which is carried by ticks. Since Lyme is most common from April to September, it’s beneficial for you to inform yourself on the subject. Mono is viral and spread through direct contact with saliva. These two can often be diagnosed interchangeably by a doctor because of the difficulty differentiating them.

The Diagnosis



Early symptoms of Lyme disease are exactly the same as mono. If untreated, symptoms may include:

Since the initial symptoms may present themselves anywhere from 3 to 30 days post tick bite, the diagnosis may often come back as mononucleosis when it is actually lyme, and vice versa. Misdiagnosing lyme or failure to treat lyme early, can result is debilitating and lasting effects on your body.

Lyme Disease

Lyme disease is often known as the bacterial disease that never truly leaves the human body and can present itself at the most inconvenient times. This is because ticks are so frequently found on our bodies and the odds that one actually carries the lyme disease bacteria is slim. Once infected, it could potentially take months or years to actually show any symptoms, and even after treatment, symptoms may linger.

How to Prevent Lyme:


The symptoms of mono and lyme disease may be very nearly identical, but the duration of mononucleosis isn’t usually as drastic. Most cases last 2 to 4 weeks with the occasional infection that incurs symptoms for months. Mononucleosis is caused by the Epstein-Barr Virus (EBV), and approximately 25% of all people infected with EBV will contract mononucleosis. Lyme disease is often misdiagnosed by a false positive EBV test which is why the two are extremely difficult to differentiate.

How to Prevent Mono

Get Tested at DOCS Urgent Care

Here at DOCS Urgent Care, we offer 24/7 care for our walk in patients. If you have even the slightest suspicion that you may have Lyme disease or mono, visit our Urgent Care Center in Fairfield, or one of our many locations closest to you. It’s better to catch Lyme or mono early on, rather than suffer from long term symptoms in the ongoing years. Here is a link for more information on our Lyme disease services.